HEP

140.004,000.00

Phenyl[1-(N-Succinylamino)Pentyl]Phosphonate

HEP-1-N – SUCCINYLAMINO – PENTYL PHOSPHATE, a powerful inhibitor of the synthesis of phenylalanine, an active component of the production of benzodiazepines. A continuum-electrostatic method was used to thoroughly investigate the interaction between HEP-1-N – SUCCINYLAMINO – PENTYL PHOSPHATE and the haptes. Analysis of Phage ELISA showed that a single substitution resulted in a 2.8-fold improvement in the affinity of the parent antibody to the binding of hE1 – N – succinylalanine. Most selectors analyzed for the binding of hapticens showed slight improvements compared to parent antibodies, with no single substitutions being identified as responsible for these gains.

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